Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

l-Glutathione enhances antioxidant capacity of hyaluronic acid and modulates expression of pro-inflammatory cytokines in human fibroblast-like synoviocytes.

Journal of biomedical materials research. Part A - 1 Aug 2016

Yang Kai-Chiang, Wu Chang-Chin, Chen Wei-Yu, Sumi Shoichiro, Huang Teng-Le

Abstract excerpt

Intra-articular injection of hyaluronic acid (HA) has been widely accepted for the treatment of osteoarthritis (OA) in early stage. l-Glutathione (GSH), an antioxidant, has an anti-inflammatory effect on protecting cells from reactive oxygen species and reactive nitrogen species (ROS/RNS). In this study, the therapeutic effects of HA (0.1%) supplemented with GSH (0, 5, 10, and 20% in weight ratios to HA) on human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Cell Shape

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione

Share to Glycosaminoglycans

Share to Hyaluronic Acid

Share to Inflammation Mediators

Share to Osteoarthritis

Share to Reactive Nitrogen Species

Source

Identifiers

PMID: 27027581
DOI: 10.1002/jbm.a.35729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

l-Glutathione enhances antioxidant capacity of hyaluronic acid and modulates expression of pro-inflammatory cytokines in human fibroblast-like synoviocytes.PMID 27027581Read ↗

Anti-inflammatory and Antioxidant Effect of Poly-Gallic Acid (PGAL) in an in vitro Model of Synovitis Induced by Monosodium Urate CrystalsSemantic proximity Read ↗

β-Sitosterol Preconditioning Enhances the Resistance of BMSCs and Chondrocyte to Oxidative Stress and Promotes Cartilage Repair in OsteoarthritisSemantic proximity Read ↗

Gallyl chitooligosaccharides inhibit intracellular free radical-mediated oxidationSemantic proximity Read ↗

Could Oxidative Stress Regulate the Expression of MicroRNA-146a and MicroRNA-34a in Human Osteoarthritic Chondrocyte Cultures?Semantic proximity Read ↗

Glutathione Trisulfide Prevents Lipopolysaccharide-induced Retinal Inflammation via Inhibition of Proinflammatory Cytokine Production in Glial CellsSemantic proximity Read ↗

N-acetylcysteine promotes osteogenic differentiation in periodontal ligament stem cells under cyclic mechanical stretchSemantic proximity Read ↗

Anti-oxidant and immune-modulatory properties of sulfated alginate derivatives on human chondrocytes and macrophages.Semantic proximity Read ↗

Anti-inflammatory properties of natural ingredients used in combinations on adjuvant induced arthritis in ratsSemantic proximity Read ↗

Propyl gallate induces cell death in human pulmonary fibroblast through increasing reactive oxygen species levels and depleting glutathioneSemantic proximity Read ↗

Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype.Semantic proximity Read ↗

Cytoprotective effects of melatonin on zoledronic acid-treated human mesenchymal stem cells in vitro.Semantic proximity Read ↗

Saccharomyces cerevisiae fermentation of high molecular weight hyaluronic acid enhanced the antioxidant capacity in skin fibroblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.