Article
Anti-oxidant and immune-modulatory properties of sulfated alginate derivatives on human chondrocytes and macrophages.
Biomaterials science - 22 Aug 2017
Kerschenmeyer Anne, Arlov Øystein, Malheiro Vera, Steinwachs Matthias, Rottmar Markus, Maniura-Weber Katharina, Palazzolo Gemma, Zenobi-Wong Marcy
Abstract excerpt
Degeneration of articular cartilage represents one of the most common causes of pain and disability in our aging society. Current treatments only address the symptoms of joint disease, but not their underlying causes which include oxidative stress and inflammation in cartilage and surrounding tissues. Sulfated biopolymers that mimic aspects of the native extracellular environment of cartilage are recently gaining...
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