Article

N-acetylcysteine promotes osteogenic differentiation in periodontal ligament stem cells under cyclic mechanical stretch

2021-03-22

Abstract excerpt

<h4>Background: </h4> Biomechanical forces are vital for the regulation of skeletal tissue. Mechanical stretch plays a vital role in osteogenic differentiation of periodontal ligament stem cells (PDLSCs) during orthodontic treatment. Cyclic mechanical stretch may trigger the up-regulated production of reactive oxygen species (ROS). ROS has a critical effect on bone cell function and the pathophysiology of bone dis...

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Literature Corpus work: fb90fe65-07bc-5e26-b6d0-f467a9bbed0f
DOI: 10.21203/rs.3.rs-338530/v1

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