Article
Cytoprotective effects of melatonin on zoledronic acid-treated human mesenchymal stem cells in vitro.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery - 1 Jul 2015
Rodríguez-Lozano Francisco Javier, García-Bernal David, Ros-Roca Maria de Los Ángeles, Algueró Maria del Carmen, Oñate-Sánchez Ricardo Elías, Camacho-Alonso Fabio, Moraleda Jose María
Abstract excerpt
OBJECTIVE: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a common clinical complication in patients receiving bisphosphonate therapy. Furthermore, melatonin has been proposed as a therapeutic drug for the oral cavity due to its antioxidant properties. This study aimed to evaluate the cytoprotective effects of melatonin on zoledronic acid (ZA)-treated human mesenchymal stem cells from periodontal...
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