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Article

Site-Specific Phosphorylation of Ikaros Induced by Low-Dose Ionizing Radiation Regulates Cell Cycle Progression of B Lymphoblast Through CK2 and AKT Activation.

International journal of radiation oncology, biology, physics - 1 Apr 2016

Cho Seong-Jun, Kang Hana, Kim Min Young, Lee Jung Eun, Kim Sung Jin, Nam Seon Young, Kim Ji Young, Kim Hee Sun, Pyo Suhkneung, Yang Kwang Hee

Abstract excerpt

PURPOSE: To determine how low-dose ionizing radiation (LDIR) regulates B lympho-proliferation and its molecular mechanism related with Ikaros, transcription factor. METHODS AND MATERIALS: Splenocytes and IM-9 cells were uniformly irradiated with various doses of a (137)Cs γ-source, and cell proliferation was analyzed. To determine the LDIR-specific phosphorylation of Ikaros, immunoprecipitation and Western blot...

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Identifiers

PMID: 27026320
DOI: 10.1016/j.ijrobp.2016.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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