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Article

Coactivation of ATM/ERK/NF-kappaB in the low-dose radiation-induced radioadaptive response in human skin keratinocytes.

Free radical biology & medicine - 1 Jun 2009

Ahmed Kazi Mokim, Nantajit Danupon, Fan Ming, Murley Jeffrey S, Grdina David J, Li Jian Jian

Abstract excerpt

Elucidating the molecular mechanism of the low-dose radiation (LDR)-mediated radioadaptive response is crucial for inventing potential therapeutic approaches to improving normal tissue protection in radiation therapy. ATM, a DNA-damage sensor, is known to activate the stress-sensitive transcription factor NF-kappaB upon exposure to ionizing radiation. This study provides evidence of the cooperative functions of...

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Source

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Identifiers

PMID: 19324081
DOI: 10.1016/j.freeradbiomed.2009.03.012
PMCID: PMC6759050

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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