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Article

Genes, Proteins, and Biological Pathways Preventing Chromothripsis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Poot Martin

Abstract excerpt

The highly complex structural genome variations chromothripsis, chromoanasynthesis, and chromoplexy are subsumed under the term chromoanagenesis, which means chromosome rebirth. Precipitated by numerous DNA double-strand breaks, they differ in number of and distances between breakpoints, associated copy number variations, order and orientation of segments, and flanking sequences at joining points. Results from...

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Source

Identifiers

PMID: 29564828
DOI: 10.1007/978-1-4939-7780-2_15

Genes

ATM
BLM
LIG4
MRE11
TREX1
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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