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Article

Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E.

International journal of geriatric psychiatry - 1 Jan 2018

Burke Shanna L, Maramaldi Peter, Cadet Tamara, Kukull Walter

Abstract excerpt

OBJECTIVE: Alzheimer's disease (AD) is a neurodegenerative disease, manifesting in clinically observable deficits in memory, thinking, and behavior that disproportionately affects older adults. Susceptibility genes, such as apolipoprotein ε4, have long been associated with an increased risk of AD diagnosis. Studies have shown associations between depression and increased risk of AD development. Furthermore,...

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PMID: 28560728
DOI: 10.1002/gps.4709
PMCID: PMC5711617

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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