Article
A family study of Alzheimer disease and early- and late-onset depression in elderly patients.
Archives of general psychiatry - 1 Feb 2001
Heun R, Papassotiropoulos A, Jessen F, Maier W, Breitner J C
Abstract excerpt
BACKGROUND: The substantial symptomatic overlap between depression and dementia in old age may be explained by common genetic vulnerability factors. METHODS: We investigated this idea by comparing the occurrence of both disorders in first-degree relatives of 78 patients with Alzheimer disease (AD), of 74 with late-onset depression (onset age of > or = 60 years), of 78 with early-onset depression, of 53 with...
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