Article
Therapeutic Rationales, Progresses, Failures, and Future Directions for Advanced Prostate Cancer
1 Jan 2016
Abstract excerpt
Patients with localized prostate cancer (PCa) have several therapeutic options with good prognosis. However, survival of patients with high-risk, advanced PCa is significantly less than patients with early-stage, organ-confined disease. Testosterone and other androgens have been directly linked to PCa progression since 1941. In this review, we chronicle the discoveries that led to modern therapeutic strategies...
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