Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma.

Oncotarget - 26 Apr 2016

Kim Joo Hoon, Lee Jae Seok, Kim Eo Jin, Park Kyu Hyun, Kim Ki Hyang, Yi Seong Yoon, Kim Han Seong, Cho Yong Jin, Shin Kyoo-Ho, Ahn Joong Bae, Hu Hyuk, Kim Kyung Sik, Choi Young Deuk, Kim Sunghoon, Lee Young Han, Suh Jin-Suck, Noh Sung Hoon, Rha Sun Young, Kim Hyo Song

Abstract excerpt

BACKGROUND: We investigated the epidemiologic characteristics and prognostic significance of PIK3CA mutations/amplifications in curative resected liposarcoma. PATIENTS AND METHODS: A total of 125 liposarcoma tissue samples were collected over a 12-year period. PIK3CA mutations and gene copy number amplifications were analyzed by pyrosequencing and fluorescence in situ hybridization (FISH). RESULTS: Nine of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Amplification

Share to In Situ Hybridization, Fluorescence

Share to Kaplan-Meier Estimate

Share to Liposarcoma

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 27016421
DOI: 10.18632/oncotarget.8240
PMCID: PMC5029721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma.PMID 27016421Read ↗

Comprehensive Immuno-Molecular Profiles for Liposarcoma: Roles of Programmed Death Ligand 1, Microsatellite Instability, and PIK3CA.Semantic proximity Read ↗

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.Semantic proximity Read ↗

Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma.Semantic proximity Read ↗

Liposarcoma: Molecular Genetics and TherapeuticsSemantic proximity Read ↗

Prognostic Implications of MDM2 and CDK4 Co-amplification in Liposarcoma: Insights from FISH analysis for Translational OncologySemantic proximity Read ↗

Clinical and Molecular Spectrum of LiposarcomaSemantic proximity Read ↗

High level of CDK4 amplification is a poor prognostic factor in well-differentiated and dedifferentiated liposarcoma.Semantic proximity Read ↗

High amplification levels of MDM2 and CDK4 correlate with poor outcome in patients with dedifferentiated liposarcoma: A cytogenomic microarray analysis of 47 casesSemantic proximity Read ↗

Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.Semantic proximity Read ↗

Oncogene mutation profiling reveals poor prognosis associated with FGFR1/3 mutation in liposarcoma.Semantic proximity Read ↗

Phosphatidylinositol-3-kinase (PI3K)/Akt Signaling is Functionally Essential in Myxoid LiposarcomaSemantic proximity Read ↗

Therapeutic opportunity of phosphodiesterase 3A modulators in myxoid liposarcomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.