Article
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.
Cancer research - 1 Apr 2011
Gobble Ryan M, Qin Li-Xuan, Brill Elliott R, Angeles Christina V, Ugras Stacy, O'Connor Rachael B, Moraco Nicole H, Decarolis Penelope L, Antonescu Cristina, Singer Samuel
Abstract excerpt
Liposarcomas are the most common type of soft tissue sarcoma but their genetics are poorly defined. To identify genes that contribute to liposarcomagenesis and serve as prognostic candidates, we undertook expression profiling of 140 primary liposarcoma samples, which were randomly split into training set (n = 95) and test set (n = 45). A multigene predictor for distant recurrence-free survival (DRFS) was...
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