Article
[Clinical and laboratory characteristics and treatment option for Philadelphia positive acute lymphoblastic leukemia patients with ABL kinase domain mutations].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Feb 2016
Cai Wenzhi, Liu Bin, Xu Yang, Chen Suning, Sun Aining, He Jun, Shen Hongjie, Wu Depei
Abstract excerpt
OBJECTIVE: To clarify the clinical, cytogenetical and molecular characteristics and prognosis of Ph(+) ALL patients with ABL kinase domain mutations (ABL-KDMs), and to evaluate the therapeutic value of allogeneic hematopoietic stem cell transplantation (allo-HSCT) combined with tyrosine kinase inhibitor (TKI) in these patients. METHODS: Retrospective analysis of clinical features, molecular genetic...
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