Article
[The different characteristics of ABL kinase domain mutation in the Chinese Han nationality imatinib resistant Philadelphia chromosome-positive acute lymphoblastic leukemia and chronic myeloid leukemia].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Jan 2013
Shen Hong-jie, He Jun, Qiu Qiao-cheng, Cen Jian-nong, Pan Jin-lan, Yao Li, Ding Zi-xuan, Chen Yan, Chen Zi-xing
Abstract excerpt
OBJECTIVE: To identify the distribution and differentiation of ABL kinase domain mutation in the Chinese Han nationality imatinib resistant chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL). METHODS: Bone marrow or peripheral blood samples of 112 imatinib resistant CML patients and 21 Ph(+)ALL patients were obtained from the first affiliated hospital of...
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