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Article

Spontaneous shaker rat mutant - a new model for X-linked tremor/ataxia.

Disease models & mechanisms - 1 May 2016

Figueroa Karla P, Paul Sharan, Calì Tito, Lopreiato Raffaele, Karan Sukanya, Frizzarin Martina, Ames Darren, Zanni Ginevra, Brini Marisa, Dansithong Warunee, Milash Brett, Scoles Daniel R, Carafoli Ernesto, Pulst Stefan M

Abstract excerpt

The shaker rat is an X-linked recessive spontaneous model of progressive Purkinje cell (PC) degeneration exhibiting a shaking ataxia and wide stance. Generation of Wistar Furth (WF)/Brown Norwegian (BN) F1 hybrids and genetic mapping of F2 sib-sib offspring using polymorphic markers narrowed the candidate gene region to 26 Mbp denoted by the last recombinant genetic marker DXRat21 at 133 Mbp to qter (the end of...

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Share to Cerebellar Ataxia
Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27013529
DOI: 10.1242/dmm.022848
PMCID: PMC4892658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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