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Article

Adaptive tolerance to a pathogenic fungus drives major histocompatibility complex evolution in natural amphibian populations.

Proceedings. Biological sciences - 30 Mar 2016

Savage Anna E, Zamudio Kelly R

Abstract excerpt

Amphibians have been affected globally by the disease chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis (Bd), and we are just now beginning to understand how immunogenetic variability contributes to disease susceptibility. Lineages of an expressed major histocompatibility complex (MHC) class II locus involved in acquired immunity are associated with chytridiomycosis susceptibility in...

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Identifiers

PMID: 27009220
DOI: 10.1098/rspb.2015.3115
PMCID: PMC4822461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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