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Article

Divergent allele advantage in the MHC and amphibian emerging infectious disease.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2023

Fu Minjie, Eimes John A, Waldman Bruce

Abstract excerpt

Genetic variation in the major histocompatibility complex (MHC) may be associated with resistance to the amphibian chytrid fungus Batrachochytrium dendrobatidis (Bd). The pathogen originated in Asia, then spread worldwide, causing amphibian population declines and species extinctions. We compared the expressed MHC IIβ1 alleles of a Bd-resistant species, Bufo gargarizans, from South Korea with those of a...

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PMID: 36990307
DOI: 10.1016/j.meegid.2023.105429

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