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Article

MHC genotypes associate with resistance to a frog-killing fungus.

Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2011

Savage Anna E, Zamudio Kelly R

Abstract excerpt

The emerging amphibian disease chytridiomycosis is caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd). Amphibian populations and species differ in susceptibility to Bd, yet we know surprisingly little about the genetic basis of this natural variation. MHC loci encode peptides that initiate acquired immunity in vertebrates, making them likely candidates for determining disease susceptibility....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21949385
DOI: 10.1073/pnas.1106893108
PMCID: PMC3189034

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