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Article

Major histocompatibility complex based resistance to a common bacterial pathogen of amphibians.

PloS one - 16 Jul 2008

Barribeau Seth M, Villinger Jandouwe, Waldman Bruce

Abstract excerpt

Given their well-developed systems of innate and adaptive immunity, global population declines of amphibians are particularly perplexing. To investigate the role of the major histocompatibility complex (MHC) in conferring pathogen resistance, we challenged Xenopus laevis tadpoles bearing different combinations of four MHC haplotypes (f, g, j, and r) with the bacterial pathogen Aeromonas hydrophila in two...

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Identifiers

PMID: 18629002
DOI: 10.1371/journal.pone.0002692
PMCID: PMC2443284

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