Article
Effect of rs1063843 in the CAMKK2 gene on the dorsolateral prefrontal cortex.
Human brain mapping - 1 Jul 2016
Yu Ping, Chen Xiongying, Zhao Wan, Zhang Zhifang, Zhang Qiumei, Han Bingqian, Zhai Jinguo, Chen Min, Du Boqi, Deng Xiaoxiang, Ji Feng, Wang Chuanyue, Xiang Yu-Tao, Li Dawei, Wu Hongjie, Li Jun, Dong Qi, Chen Chuansheng
Abstract excerpt
Recently, a single nucleotide polymorphism (SNP) in the CAMKK2 gene (rs1063843) was found to be associated with lower expression of the gene in the dorsolateral prefrontal cortex (DLPFC) and with schizophrenia (SCZ) and deficits in working memory and executive function. However, the brain mechanism underlying this association is poorly understood. A functional magnetic resonance imaging (fMRI) study (N = 84...
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