Article
Precursor miR-499a Variant but not miR-196a2 is Associated with Rheumatoid Arthritis Susceptibility in an Egyptian Population.
Molecular diagnosis & therapy - 1 Jun 2016
Toraih Eman A, Ismail Nesreen M, Toraih Ahmed A, Hussein Mohammad H, Fawzy Manal S
Abstract excerpt
INTRODUCTION: Rheumatoid arthritis (RA) has a complex component induced by several genes that interact together with environmental and hormonal factors. We aimed to investigate the association of miR-196a2 rs11614913 (C/T) and miR-499a rs3746444 (A/G) polymorphisms and their combination with RA susceptibility and disease activity in an Egyptian population, and to evaluate their impact on methotrexate drug...
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