Article
Possible use of miRNAs-146a and -499 expression and their polymorphisms as diagnostic markers for rheumatoid arthritis.
Molecular and cellular biochemistry - 1 Dec 2018
Ayeldeen Ghada, Nassar Yasser, Ahmed Hanan, Shaker Olfat, Gheita Tamer
Abstract excerpt
Rheumatoid arthritis (RA) is a systemic autoimmune disorder affecting the peripheral joints. Different microRNAs had been investigated in RA including miRNA-146a meanwhile, miRNA-499 there were no studies to prove its expression in RA serum samples. This study was performed to investigate expression of both miRNAs-146a and -499 and their polymorphisms in Egyptian patients with RA and to evaluate their...
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