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Article

Association of MiRNA-146a, MiRNA-499, IRAK1 and PADI4 Polymorphisms with Rheumatoid Arthritis in Egyptian Population.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2018

Shaker Olfat Gamil, El Boghdady Noha Ahmed, El Sayed Abeer El-Dessouki

Abstract excerpt

BACKGROUND/AIMS: Rheumatoid arthritis (RA) is a systemic autoimmune disease affecting up to 1% of the population worldwide. The aim of the present study was to investigate whether miRNA-146a rs2910164, miRNA-499 rs3746444, IRAK1 rs3027898 and PADI4 rs1748033 polymorphisms are associated with susceptibility to RA in Egyptians and whether they influence disease severity and activity. METHODS: The study was...

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Share to Arthritis, Rheumatoid
Share to Egypt
Share to Genetic Predisposition to Disease
Share to Interleukin-1 Receptor-Associated Kinases
Share to MicroRNAs
Share to Polymorphism, Single Nucleotide
Share to Protein-Arginine Deiminase Type 4
Share to Protein-Arginine Deiminases

Source

Identifiers

PMID: 29734142
DOI: 10.1159/000489592

Genes

IRAK1
PADI4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of MiRNA-146a, MiRNA-499, IRAK1 and PADI4 Polymorphisms with Rheumatoid Arthritis in Egyptian Population.PMID 29734142Read ↗

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