Article
[The pathogenicity of somatic mutation to common tumors and developmental malformation of the nervous system].
Yi chuan = Hereditas - 1 Mar 2016
Liu Fang, Song Xiao-zhen, Xie Hua, Chen Xiao-li
Abstract excerpt
In the course of development, both endogenous and exogenous factors can cause DNA damage, which resulted in somatic mutations. It is recongnized that somatic mutations are the causation of many nervous cancers, the pathogenicity of somatic mutation in developmental malformation of nervous system is unknown yet. With the development of next generation sequencing (NGS), especially the clinical application of the...
Topics
- Animals
- Humans
- Mutation
- Neoplasms
- Nervous System
- Nervous System Malformations