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Article

Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.

Cardiovascular research - 1 Jun 2016

Alesutan Ioana, Feger Martina, Tuffaha Rashad, Castor Tatsiana, Musculus Katharina, Buehling Salvatore S, Heine Christian L, Kuro-O Makoto, Pieske Burkert, Schmidt Kurt, Tomaschitz Andreas, Maerz Winfried, Pilz Stefan, Meinitzer Andreas, Voelkl Jakob, Lang Florian

Abstract excerpt

AIMS: Reduced homoarginine plasma levels are associated with unfavourable cardiovascular outcome in chronic kidney disease (CKD). Cardiovascular events in CKD are fostered by vascular calcification, an active process promoted by hyperphosphatemia and involving osteo-/chondrogenic transformation of vascular smooth muscle cells (VSMCs). The present study explored the effect of homoarginine on phosphate-induced...

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Source

Identifiers

PMID: 27001421
DOI: 10.1093/cvr/cvw062

Genes

ALPL
MSX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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