Article
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.
Psychological medicine - 1 Jun 2016
Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta K L, Terracciano A, Nalls M A, Tanaka T, Hek K, Fornage M, Wellmann J, Cornelis M C, Ollila H M, Yu L, Smith J A, Pilling L C, Isaacs A, Palotie A, Zhuang W V, Zonderman A, Faul J D, Sutin A, Meirelles O, Mulas A, Hofman A, Uitterlinden A, Rivadeneira F, Perola M, Zhao W, Salomaa V, Yaffe K, Luik A I, Liu Y, Ding J, Lichtenstein P, Landén M, Widen E, Weir D R, Llewellyn D J, Murray A, Kardia S L R, Eriksson J G, Koenen K, Magnusson P K E, Ferrucci L, Mosley T H, Cucca F, Oostra B A, Bennett D A, Paunio T, Berger K, Harris T B, Pedersen N L, Murabito J M, Tiemeier H, van Duijn C M, Räikkönen K
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is moderately heritable, however genome-wide association studies (GWAS) for MDD, as well as for related continuous outcomes, have not shown consistent results. Attempts to elucidate the genetic basis of MDD may be hindered by heterogeneity in diagnosis. The Center for Epidemiological Studies Depression (CES-D) scale provides a widely used tool for measuring depressive...
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