Article
Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development.
The Journal of investigative dermatology - 1 Aug 2016
Dauber Katherine L, Perdigoto Carolina N, Valdes Victor J, Santoriello Francis J, Cohen Idan, Ezhkova Elena
Abstract excerpt
Polycomb repressive complex 2 (PRC2) is an essential regulator of cell physiology. Although there have been numerous studies on PRC2 function in somatic tissue development and stem cell control, these have focused on the loss of a single PRC2 subunit. Recent studies, however, have shown that PRC2 subunits may function independently of the PRC2 complex. To investigate the function of PRC2 in the control of skin...
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