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Article

Effect of glucocorticoids on the activity, expression and proximal promoter of type II deiodinase in rat brown adipocytes.

Molecular and cellular endocrinology - 15 Jun 2016

Martinez-deMena Raquel, Calvo Rosa-Maria, Garcia Laura, Obregon Maria Jesus

Abstract excerpt

Triiodothyronine (T3) is important for thermogenesis in brown adipose tissue (BAT). Type II deiodinase (DIO2) produces T3 required for intracellular needs in BAT. Brown adipocytes in culture require T3 for the adrenergic stimulation of DIO2. Glucocorticoids induce adipocyte differentiation (lipogenesis). We investigated the regulation of DIO2 activity, Dio2 mRNA and Dio2 promoter activity by glucocorticoids in...

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Source

Identifiers

PMID: 26994513
DOI: 10.1016/j.mce.2016.03.021

Genes

DIO2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of glucocorticoids on the activity, expression and proximal promoter of type II deiodinase in rat brown adipocytes.PMID 26994513Read ↗

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