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Article

Quantitation of fetal DNA fraction in maternal plasma using circulating single molecule amplification and re-sequencing technology (cSMART).

Clinica chimica acta; international journal of clinical chemistry - 1 May 2016

Song Yijun, Zhou Xiya, Huang Saiqiong, Li Xiaohong, Qi Qingwei, Jiang Yulin, Liu Yiqian, Ma Chengcheng, Li Zhifeng, Xu Mengnan, Cram David S, Liu Juntao

Abstract excerpt

BACKGROUND: Calculation of the fetal DNA fraction (FF) is important for reliable and accurate noninvasive prenatal testing (NIPT) for fetal genetic abnormalities. The aim of the study was to develop and validate a novel method for FF determination. METHODS: FF was calculated using the chromosome Y (ChrY) sequence read assay and by circulating single molecule amplification and re-sequencing technology of 76...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26993877
DOI: 10.1016/j.cca.2016.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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