Article
Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future.
Oncotarget - 31 May 2016
Mao Xiao-Yuan, Dai Jin-Xiang, Zhou Hong-Hao, Liu Zhao-Qian, Jin Wei-Lin
Abstract excerpt
Although brain tumors have been known tremendously over the past decade, there are still many problems to be solved. The etiology of brain tumors is not well understood and the treatment remains modest. There is in great need to develop a suitable brain tumor models that faithfully mirror the etiology of human brain neoplasm and subsequently get more efficient therapeutic approaches for these disorders. In this...
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