Rare UNC13B variations and risk of schizophrenia: Whole-exome sequencing in a multiplex family and follow-up resequencing and a case-control study.

doi:10.1002/ajmg.b.32444

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Article

Rare UNC13B variations and risk of schizophrenia: Whole-exome sequencing in a multiplex family and follow-up resequencing and a case-control study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2016

Egawa Jun, Hoya Satoshi, Watanabe Yuichiro, Nunokawa Ayako, Shibuya Masako, Ikeda Masashi, Inoue Emiko, Okuda Shujiro, Kondo Kenji, Saito Takeo, Kaneko Naoshi, Muratake Tatsuyuki, Igeta Hirofumi, Iwata Nakao, Someya Toshiyuki

Abstract excerpt

Rare genomic variations inherited in multiplex schizophrenia families are suggested to play a role in the genetic etiology of the disease. To identify rare variations with large effects on the risk of developing schizophrenia, we performed whole-exome sequencing (WES) in two affected and one unaffected individual of a multiplex family with 10 affected individuals. We also performed follow-up resequencing of the...

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PMID: 26990377
DOI: 10.1002/ajmg.b.32444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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