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Novel missense SETD1A variants in Japanese patients with schizophrenia: Resequencing and association analysis.

Psychiatry research - 1 Apr 2022

Morikawa Ryo, Watanabe Yuichiro, Igeta Hirofumi, Arta Reza K, Ikeda Masashi, Okazaki Satoshi, Hoya Satoshi, Saito Takeo, Otsuka Ikuo, Egawa Jun, Tanifuji Takaki, Iwata Nakao, Someya Toshiyuki

Abstract excerpt

SETD1A has been identified as a substantial risk gene for schizophrenia. To further investigate the role of SETD1A in the genetic etiology of schizophrenia in the Japanese population, we performed resequencing and association analyses. First, we resequenced the SETD1A coding regions of 974 patients with schizophrenia. Then, we genotyped variants, prioritized via resequencing, in 2,027 patients with schizophrenia...

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PMID: 35235885
DOI: 10.1016/j.psychres.2022.114481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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