Article
Use of genetically encoded, light-gated ion translocators to control tumorigenesis.
Oncotarget - 12 Apr 2016
Chernet Brook T, Adams Dany S, Lobikin Maria, Levin Michael
Abstract excerpt
It has long been known that the resting potential of tumor cells is depolarized relative to their normal counterparts. More recent work has provided evidence that resting potential is not just a readout of cell state: it regulates cell behavior as well. Thus, the ability to control resting potential in vivo would provide a powerful new tool for the study and treatment of tumors, a tool capable of revealing...
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