Article
Profiling of potential driver mutations in sarcomas by targeted next generation sequencing.
Cancer genetics - 1 Apr 2016
Andersson Carola, Fagman Henrik, Hansson Magnus, Enlund Fredrik
Abstract excerpt
Comprehensive genetic profiling by massively parallel sequencing, commonly known as next generation sequencing (NGS), is becoming the foundation of personalized oncology. For sarcomas very few targeted treatments are currently in routine use. In clinical practice the preoperative diagnostic workup of soft tissue tumours largely relies on core needle biopsies. Although mostly sufficient for histopathological...
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