Article
Introduction and impact of routine whole genome sequencing in the diagnosis and management of sarcoma.
British journal of cancer - 1 Sept 2024
Watkins James A, Trotman Jamie, Tadross John A, Harrington Jennifer, Hatcher Helen, Horan Gail, Prewett Sarah, Wong Han H, McDonald Sarah, Tarpey Patrick, Roberts Thomas, Su Jing, Tischkowitz Marc, Armstrong Ruth, Amary Fernanda, Sosinsky Alona
Abstract excerpt
BACKGROUND: Sarcomas are diverse neoplasms with highly variable histological appearances in which diagnosis is often challenging and management options for metastatic/unresectable disease limited. Many sarcomas have distinctive molecular alterations, but the range of alterations is large, variable in type and rapidly increasing, meaning that testing by limited panels is unable to capture the broad spectrum of...
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