A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis.

doi:10.1093/rheumatology/kew035

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Article

A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis.

Rheumatology (Oxford, England) - 1 Jun 2016

Julià Antonio, González Isidoro, Fernández-Nebro Antonio, Blanco Francisco, Rodriguez Luis, González Antonio, Cañete Juan D, Maymó Joan, Alperi-López Mercedes, Olivé Alejandro, Corominas Héctor, Martínez-Taboada Víctor, Erra Alba, Sánchez-Fernández Simón, Alonso Arnald, Lopez-Lasanta Maria, Tortosa Raül, Codó Laia, Gelpi Josep Lluis, García-Montero Andres C, Bertranpetit Jaume, Absher Devin, Bridges S Louis, Myers Richard M, Tornero Jesus, Marsal Sara

Abstract excerpt

OBJECTIVE: RA patients with serum ACPA have a strong and specific genetic background. The objective of the study was to identify new susceptibility genes for ACPA-positive RA using a genome-wide association approach. METHODS: A total of 924 ACPA-positive RA patients with joint damage in hands and/or feet, and 1524 healthy controls were genotyped in 582 591 single-nucleotide polymorphisms (SNPs) in the discovery...

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PMID: 26983453
DOI: 10.1093/rheumatology/kew035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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