Article
Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease.
Annals of the rheumatic diseases - 1 Jun 2010
Robinson James I, Barrett Jennifer H, Taylor John C, Naven Marc, Corscadden Diane, Barton Anne, Wilson Anthony G, Emery Paul, Isaacs John D, Morgan Ann W
Abstract excerpt
OBJECTIVES: Genome-wide association studies in rheumatoid arthritis (RA) have failed to examine the FCGR gene cluster because of the confounding effects of segmental duplication. This study aimed to replicate previous candidate gene studies that had identified a significant association between the FCGR3A-158V allele and RA and then sought to estimate specific subgroup effects. METHODS: FCGR3A-158F/V genotyping...
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