Article
Genome-wide haplotype association analysis and gene prioritization identify CCL3 as a risk locus for rheumatoid arthritis.
International journal of immunogenetics - 1 Aug 2010
Zhang R, Sun P, Jiang Y, Chen Z, Huang C, Zhang X, Zhang R
Abstract excerpt
Rheumatoid arthritis (RA) is a common autoimmune disease caused by a complex interaction of multiple genetic variants and environmental factors. The association between RA and genetic susceptibility loci has been observed in many different populations, and most studies have focused on univariate analyses of single nucleotide polymorphisms. We performed a genome-wide haplotype association study and prioritized...
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