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Article

Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ.

Investigative ophthalmology & visual science - 1 Mar 2016

Ji Xiaojie, Liu Ye, Hurd Ron, Wang Jieping, Fitzmaurice Bernie, Nishina Patsy M, Chang Bo

Abstract excerpt

PURPOSE: Retinal detachments (RDs), a separation of the light-sensitive tissue of the retina from its supporting layers in the posterior eye, isolate retinal cells from their normal supply of nourishment and can lead to their deterioration and death. We identified a new, spontaneous murine model of exudative retinal detachment, nm3342 (new mutant 3342, also referred to as rpea1: retinal pigment epithelium atrophy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Photoreceptor Cells, Vertebrate

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Share to Tomography, Optical Coherence

Source

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Identifiers

PMID: 26978024
DOI: 10.1167/iovs.15-17495
PMCID: PMC4794085

Genes

RPE
ERG
PRKCQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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