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Article

Metastasis to Bone in Human Cancer Is Associated with Loss of Occludin Expression.

Anticancer research - 1 Mar 2016

Martin Tracey A, Jordan Nicola, Davies Eleri L, Jiang Wen G

Abstract excerpt

BACKGROUND: Occludin is an integral membrane protein localised at tight junctions (TJ). There is no consensus regarding its paramount role in TJ. In previous work we showed that occludin is aberrantly expressed in both human breast tissues and cancer cell lines. This study demonstrates a link to bone metastasis in human cancer. MATERIALS AND METHODS: Primary breast tumours (n=124) and matched normal tissues...

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PMID: 26977027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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