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Article

Vitamin D regulates the phenotype of human breast cancer cells.

Differentiation; research in biological diversity - 1 Mar 2007

Pendás-Franco Natalia, González-Sancho José Manuel, Suárez Yajaira, Aguilera Oscar, Steinmeyer Andreas, Gamallo Carlos, Berciano María T, Lafarga Miguel, Muñoz Alberto

Abstract excerpt

1alpha,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), the most active vitamin D metabolite, regulates proliferation, survival, and differentiation in many cell types. 1,25(OH)(2)D(3) and several less calcemic analogs are in clinical trials against various neoplasias. We studied the effects of 1,25(OH)(2)D(3) on a panel of human breast cancer cells, which show similar vitamin D receptor (VDR) content but variable...

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Identifiers

PMID: 17288543
DOI: 10.1111/j.1432-0436.2006.00131.x

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VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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