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Article

Distinct Histomorphology in Molecular Subgroups of Glioblastomas in Young Patients.

Journal of neuropathology and experimental neurology - 1 May 2016

Neumann Julia E, Dorostkar Mario M, Korshunov Andrey, Mawrin Christian, Koch Arend, Giese Armin, Schüller Ulrich

Abstract excerpt

Glioblastomas (GBMs) are malignant brain tumors that can be divided into different molecular subtypes based on genetics, global gene expression, and methylation patterns. Among these subgroups, "IDH" GBMs carry mutations within IDH1 or IDH2 The "K27" and "G34" subgroups are characterized by distinct mutations within Histone 3 (H3). These subtypes can be identified by sequencing methods and are particularly found...

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Source

Identifiers

PMID: 26975364
DOI: 10.1093/jnen/nlw015

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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