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Article

Clinical relevance of the HCV protease inhibitor-resistant mutant viral load assessed by ultra-deep pyrosequencing in treatment failure.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2016

Mohamed Sofiane, Bourliere Marc, Benali Souad, Oules Valerie, Castellani Paul, Khiri Hacène, Camus Claire, Penaranda Guillaume, Chiche Laurent, Gonzalez Dimitri, Sayada Chalom, Olive Daniel, Halfon Philippe

Abstract excerpt

BACKGROUND: The detection of low frequency mutants in patients with hepatitis C virus (HCV) receiving direct-acting antivirals (DAAs) is still debated. The clinical relevance of the mutant viral load has not yet been evaluated. OBJECTIVES: To assess the viral load of resistance associated variants (RAVs) in patients at different time points, including the baseline, virological failure and one year after the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26971166
DOI: 10.1016/j.jcv.2016.02.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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