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Article

Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer.

Cancer letters - 10 Oct 2016

Bauer Christian, Kühnemuth Benjamin, Duewell Peter, Ormanns Steffen, Gress Thomas, Schnurr Max

Abstract excerpt

Pancreatic cancer is one of the most aggressive malignancies and has been considered poorly immunogenic for decades. However, this characterization might be over-simplistic. A more sophisticated approach is needed in order to develop new treatment strategies. In this review, we will focus on T cell exhaustion as a phenomenon of immune failure that is a useful paradigm to characterize immunosuppressive effects....

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Source

Identifiers

PMID: 26968250
DOI: 10.1016/j.canlet.2016.02.057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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