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Article

Targeting tumor tolerance: A new hope for pancreatic cancer therapy?

Pharmacology & therapeutics - 1 Oct 2016

Delitto Daniel, Wallet Shannon M, Hughes Steven J

Abstract excerpt

With a 5-year survival rate of just 8%, pancreatic cancer (PC) is projected to be the second leading cause of cancer deaths by 2030. Most PC patients are not eligible for surgery with curative intent upon diagnosis, emphasizing a need for more effective therapies. However, PC is notoriously resistant to chemoradiation regimens. As an alternative, immune modulating strategies have recently achieved success in...

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PMID: 27343757
DOI: 10.1016/j.pharmthera.2016.06.008

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