Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acromegaly Is More Severe in Patients With AHR or AIP Gene Variants Living in Highly Polluted Areas.

The Journal of clinical endocrinology and metabolism - 1 Apr 2016

Cannavo S, Ragonese M, Puglisi S, Romeo P D, Torre M L, Alibrandi A, Scaroni C, Occhi G, Ceccato F, Regazzo D, De Menis E, Sartorato P, Arnaldi G, Trementino L, Trimarchi F, Ferrau F

Abstract excerpt

CONTEXT: An increased prevalence of acromegaly was found some years ago in a highly polluted area in North-Eastern Sicily, where high concentration of nonmethane hydrocarbons, volatile organic compounds, and cadmium was found. Aryl hydrocarbon receptor (AHR) pathway has a key role in detoxification of these compounds and in tumorigenesis. OBJECTIVE: We correlated the occurrence of AHR and/or AHR-interacting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acromegaly
Share to Environmental Pollution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Human Growth Hormone

Share to Insulin-Like Growth Factor I

Share to Intracellular Signaling Peptides and Proteins

Share to Receptors, Aryl Hydrocarbon

Source

Identifiers

PMID: 26963951
DOI: 10.1210/jc.2015-4191

Genes

AHR
AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acromegaly Is More Severe in Patients With AHR or AIP Gene Variants Living in Highly Polluted Areas.PMID 26963951Read ↗

Acromegaly, genetic variants of the aryl hydrocarbon receptor pathway and environmental burden.Semantic proximity Read ↗

Increased frequency of the rs2066853 variant of aryl hydrocarbon receptor gene in patients with acromegaly.Semantic proximity Read ↗

Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.Semantic proximity Read ↗

Familial acromegaly due to aryl hydrocarbon receptor-interacting protein (AIP) gene mutation in a Turkish cohort.Semantic proximity Read ↗

Adrenal lesions in acromegaly: do metabolic aspects and aryl hydrocarbon receptor interacting protein gene have a role? Evaluation at baseline and after long-term follow-up.Semantic proximity Read ↗

Risk category system to identify pituitary adenoma patients with AIP mutationsSemantic proximity Read ↗

AIP mutations impair AhR signaling in pituitary adenoma patients fibroblasts and in GH3 cells.Semantic proximity Read ↗

Aryl hydrocarbon receptor-interacting protein and acromegaly.Semantic proximity Read ↗

Familial Isolated Pituitary Adenomas (FIPA) and Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) GeneSemantic proximity Read ↗

An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene.Semantic proximity Read ↗

Novel AIP mutation in exon 6 causing acromegaly in a German family.Semantic proximity Read ↗

Frequency of AIP gene mutations in young patients with acromegaly: a registry-based study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.