Article
Genetic Variants in Folate and Cobalamin Metabolism-Related Genes in Nonsyndromic Cleft Lip and/or Palate.
Brazilian dental journal - 1 Jan 2000
Waltrick-Zambuzzi Márcia, Tannure Patricia Nivoloni, Vieira Thays Cristine Dos Santos, Antunes Leonardo Santos, Romano Fábio Lourenço, Zambuzzi Willian Fernando, Granjeiro José Mauro, Küchler Erika Calvano
Abstract excerpt
The aim of this study was to evaluate the association of the polymorphisms in TCN2 (rs1801198) gene and in MTRR (rs1801394) gene with nonsyndromic cleft lip and/or palate (NSCL/P) in a Brazilian population. Genomic DNA was extracted from buccal cells. The polymorphisms in TCN2 (rs1801198) and MTRR (rs1801394) genes were genotyped by carrying out real-time PCR and Taqman assay. Chi-square test was used to...
Read the complete abstract on PubMed