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Article

Drosophila beta spectrin functions independently of alpha spectrin to polarize the Na,K ATPase in epithelial cells.

The Journal of cell biology - 1 May 2000

Dubreuil R R, Wang P, Dahl S, Lee J, Goldstein L S

Abstract excerpt

Spectrin has been proposed to function as a sorting machine that concentrates interacting proteins such as the Na,K ATPase within specialized plasma membrane domains of polarized cells. However, little direct evidence to support this model has been obtained. Here we used a genetic approach to directly test the requirement for the beta subunit of the alphabeta spectrin molecule in morphogenesis and function of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10791978
DOI: 10.1083/jcb.149.3.647
PMCID: PMC2174857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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