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Article

Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy.

Journal of biomolecular screening - 1 Dec 2013

Carlson Coby, Koonce Chad, Aoyama Natsuyo, Einhorn Shannon, Fiene Steve, Thompson Arne, Swanson Brad, Anson Blake, Kattman Steven

Abstract excerpt

A major hurdle for cardiovascular disease researchers has been the lack of robust and physiologically relevant cell-based assays for drug discovery. Derivation of cardiomyocytes from human-induced pluripotent stem (iPS) cells at high purity, quality, and quantity enables the development of relevant models of human cardiac disease with source material that meets the demands of high-throughput screening (HTS). Here...

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PMID: 24071917
DOI: 10.1177/1087057113500812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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