A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.

doi:10.1158/1055-9965.EPI-15-0144

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Article

A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2016

Bei Jin-Xin, Su Wen-Hui, Ng Ching-Ching, Yu Kai, Chin Yoon-Ming, Lou Pei-Jen, Hsu Wan-Lun, McKay James D, Chen Chien-Jen, Chang Yu-Sun, Chen Li-Zhen, Chen Ming-Yuan, Cui Qian, Feng Fu-Tuo, Feng Qi-Shen, Guo Yun-Miao, Jia Wei-Hua, Khoo Alan Soo-Beng, Liu Wen-Sheng, Mo Hao-Yuan, Pua Kin-Choo, Teo Soo-Hwang, Tse Ka-Po, Xia Yun-Fei, Zhang Hongxin, Zhou Gang-Qiao, Liu Jian-Jun, Zeng Yi-Xin, Hildesheim Allan

Abstract excerpt

BACKGROUND: Genetic loci within the major histocompatibility complex (MHC) have been associated with nasopharyngeal carcinoma (NPC), an Epstein-Barr virus (EBV)-associated cancer, in several GWAS. Results outside this region have varied. METHODS: We conducted a meta-analysis of four NPC GWAS among Chinese individuals (2,152 cases; 3,740 controls). Forty-three noteworthy findings outside the MHC region were...

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Identifiers

PMID: 26545403
DOI: 10.1158/1055-9965.EPI-15-0144
PMCID: PMC4713263

Genes

TERT
IMPACT
MECOM
TNFRSF19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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